Aminex's PBT Therapy promises to provide long-lived, robust effects. Cancer has touched everyone’s life. Standard therapy for this disease involves attempts at burning, bleeding or poisoning the tumors selectively while leaving normal tissues unaffected. While it is known that in many cases, the primary tumors can be effectively eliminated, it is the secondary or reoccurrence of metastatic tumors to distant places in the body that ultimately are the real killers. By unleashing the specificity of the immune system against the tumor, we at Aminex Therapeutics believe we have discovered a better way to treat cancer.

            It has been known for more than 50 years that tumors have a higher concentration of the cellular metabolites known as the polyamines. Using the specificity of Aminex’s PBT (Polyamine-Based Therapy) approach, the levels of these metabolites are reduced to levels similar to those in normal tissues. While exploring the effect of its PBT approach in animal models, Aminex scientists made the profound discovery that an immune reaction against the tumor was initiated, resulting in the complete disappearance of established tumors in these animals. Equally critical was the observation that when PBT therapy was stopped; the tumors did not re-grow. With a small-molecule based immunotherapy approach that promises to also be effective against metastases, we believe that PBT therapy has the potential for a permanent cure.